4F-MPH 2g

Research Chemical Shop is closed on holiday until the 24th of August. Research Chemicals shipments will resume then. All other sections of our store remain fully functional!

Research Chemicals sold at Express Highs are not intended for human consumption. They are not intended to diagnose, cure or prevent any disease and are not medicine. Use only in a suitable, controlled chemical research environment or laboratory. Always wear appropriate personal protective equipment (PPE) in accordance with chemical safety standards. Keep out of reach of unauthorized persons and minors.

Research Chemical Shop will be on holiday from 31st of July until the 14th of August.
This time will be used for us to extend our variety and add many more Research Chemicals to this category.
You may pre order the products and they will be shipped on August 14th 2023.

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IUPAC name: Methyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate HCl

CAS number: 1354631-33-6

Purity: min 98.5%

Appearance: White to off-white powder

4F-MPH (4-Fluoromethylphenidate) is a research chemical that can act as a better dopamine reuptake inhibitor than analogue methylphenidate. It was first developed by chemists as an ethylphenidate replacement.

As it is structurally related to methylphenidate, it might be of some interest to researchers studying similar compounds.Normally, a batch of 4F-MCH is available as white powder, and like all other research chemicals, is of at least 98.5 percent purity confirmed by independent analysis.

It has been formulated strictly for research, forensic or chemical reference purposes only. It’s not intended for human consumption.

A study in 2009 found that para- and meta-substituted compounds with many electron-withdrawing substituents in some threo-isomers of methylphenidate have increased its binding potency. Compounds containing chlorine, fluorine, methyl groups and bromine were reported to be much more potent than methylphenidate. Due to presence of fluorine, 4F-MPH has better binding potency as dopamine reuptake inhibitor. It reported as having ED52mg/kg or 0.28 and also a relative potency of 3.37 to methylphenidate.

4F-MPH effectively boosts dopamine neurotransmitters in the brain and acts as effective dopamine reuptake inhibitor (DRI). It blocks or binds transporter proteins that remove most of the monoamines from synaptic cleft, resulting in better accumulation of dopamine within the brain mass.

Previously many compounds with DRI action have been widely used clinically. They are: dexmethylphenidate, amineptine, fencamfamine, difemetorex, nomifensine, medifoxamine, pyrovalenrone, and prolintane. Though all these compounds may have different modes of action, the mode of action and pharmacotherapeutic use of 4F-MPH is yet to be fully discovered by scientific community.

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This product is not for human consumption, for research and reference use only.

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